Vial filling machines from Vanrx provide lower risk for liquid and lyophilized drug products from development through commercialization.

Pharmaceutical vial filling machines

Standardization or flexibility? Robust aseptic process or speed to market? Our customers say yes, ja, oui and 是.

Vanrx’s Aseptic Filling Workcells have vial filling covered, from drug development through commercialization—liquid or lyophilized. Bring your drug products to patients in vials faster and at higher quality using closed robotic workcells.


Who uses Vanrx vial filling machines?

Leading biopharma companies using Vanrx Aseptic Filling Workcells for vial filling include ADMA Biologics, Amgen, Emergent BioSolutions, FUJIFILM Diosynth Biotechnologies, Roche / Genentech, Moderna, Singota Solutions, WuXi Biologics, and Wildlife Pharmaceuticals.

Vanrx vial filling machines can fill nested, pre-sterilized ISO vials from 2R to 50R.

Super flexible

Both the Microcell Vial Filler and SA25 Aseptic Filling Workcell can fill nested, pre-sterilized ISO vials from 2R to 50R. Changeover and decontamination between products can occur in as little as 15 minutes, allowing you to fill multiple sizes faster.

Vial filling is performed by our new Vanrx Dynamic Peristaltic Pump. The pump offers a 10x improvement in variability versus conventional peristaltic pumps. The pump’s accuracy level extends down to 0.1 mL — addressing a notable weakness of conventional peristaltic pumps losing accuracy at or below 1.0 mL. Users of the pump will be able to reduce overfill parameters and achieve higher batch yields.

Vanrx vial filling machines are standardized, automated and gloveless with less risk of contamination.

Risk reduction and shorter time to market

A standardized robotic solution creates what is described as a “virtuous cycle” of automation and reduced risk. With standardization you won’t have to design a new aseptic process. We’ve done the work. The use of advanced robotics creates more control over the filling process. This results in less human error which then leads to less contamination of the drug products. Reducing the risk of contamination ultimately means lower costs associated with error and faster time to market.

Vanrx vial filling machines use nested ready-to-use vials and press-fit closures with integrated stoppers from leading primary packaging suppliers.

Nested ready-to-use vials

Reduce risk even further with the use of ready-to-use (RTU) vials with press-fit closures.

Just how are they better? Nested vials eliminate glass-to-glass contact resulting in fewer particles and cosmetic issues that cause rejects. In terms of press-fit closures they are made of plastic – goodbye aluminum! – with an integrated stopper. In one motion both the cap and stopper are sealed onto vials. With this single closure step not only is manufacturing simplified, quality is also improved.