How to fill sterile vials

Both the Microcell™ Vial Filler and SA25 Aseptic Filling Workcell can fill nested, pre-sterilized ISO vials from 2R to 50R. Automating the filling process keeps decontamination and changeover times between products low – as little as 15 minutes with Aseptic Filling Workcells from Cytiva.

Filling of nested vials inside the SA25 Aseptic Filling Workcell

Risk reduction

A standardized robotic solution creates a cycle of reduced risk compared to conventional systems. Automation results in less human error, which leads to less contamination of the drug product. This is the main regulatory focus for aseptic processing. Workcells from Cytiva support manufacturer compliance with Annex 1 and FDA guidelines for aseptic processing.

Robotic controls of the Microcell Vial Filler

Nested ready-to-use vials

Reduce risk even further with ready-to-use (RTU) vials with press-fit closures. Nested vials eliminate glass-to-glass contact resulting in fewer particles generated. Plastic press-fit closures with an integrated stopper are sealed onto vials in one fluid motion, simplifying manufacturing and maintaining product quality.

Filled and capped pharmaceutical vials in the SA25 Aseptic Filling Workcell

Discover how our 1^st to market gloveless, robotic innovative approach supports EU-ANNEX-1 and other regulatory compliance. Learn how we’ve created a standard solution for aseptic filling that delivers higher control, reduced risk of contamination and less human error, lower cost, and faster time to market.

Resources

Close-up shot of vials moving through the SA25 Aseptic Filling Workcell

Closed robotic workcells

Learn how they differ from conventional systems and how your drug product operations can benefit.

Standardization and flexibility

You don’t have to choose between the two – and they actually complement each other.

Vial, syringes and cartridge filling on the SA25 Aseptic Filling Workcell.

Gain speed to GMP filling

Learn how aseptic filling technology can give you speed advantage to GMP filling

SA25 Aseptic Filling Workcell for pharmaceutical vial, syringe and cartridge filling

Customer story: Emergent BioSolutions

How Emergent BioSolutions transitioned their commercial products to our gloveless filling platform.