Vanrx Aseptic Workcell Cluster, consisting of the SA25 Aseptic Filling Workcell, Lyophilizer Loader Workcell and Accumulator Workcell. A complete pharmaceutical filling system for producing liquid or lyophilized therapies.

Versatility for complex therapies

Extend the flexibility of the SA25 Aseptic Filling Workcell. The full Vanrx Workcell cluster supports the production of lyophilized, viral or cytotoxic therapies.

Lyophilizer Loader Workcell

Therapies remain within an ISO 5 / Grade A environment throughout the filling, freeze-drying and closing phases, with no human intervention.

The Lyo Loader uses robotics in a gloveless isolator to automate the loading and unloading of a lyophilizer. Since vials or syringes remain within their nests, there is no glass-to-glass contact, and no risk of containers falling over during loading / unloading or the lyophilization cycle.


How the Lyo Loader works

Vanrx systems use nested vials and press-fit closures with built-in stoppers. This means that dosages are unloaded by the Lyo Loader completely closed and ready for de-nesting and exterior vial washing.

Lyo Loader & Accumulator Workcell specifications



Fully automated, gloveless closed isolator


Robotic handling of nested containers (vials, syringes or cartridges), stoppers and closures


Full 316L stainless steel interior and robotics


Vapor-phase hydrogen peroxide, Clean-in-Place (CIP)

Environmental Monitoring

Automated viable and non-viable

Control System

21 CFR Part 11 compliant


Accumulator: 1.4m wide x 2.3m long x 2.4m high (4.6′ x 7.5′ x 7.9′)

Lyophilizer Loader: 1.4m wide x 3.4m long x 2.4m high (4.6′ x 11.1′ x 7.9′)

Accumulator Workcell

The Accumulator Workcell can perform several functions that complement the operation of the SA25 Aseptic Filling Workcell and Lyophilizer Loader Workcell:

  • Act as a buffer in making products that are dangerous to operators, such as cytotoxic or viral therapies;
  • Accumulate finished product, which can be removed by an operator while the SA25 Aseptic Filling Workcell continues to fill and close containers;
  • Allow the removal of waste via a one-way port.

The Accumulator Workcell uses robotics identical to those in other Vanrx systems to handle nested syringes, vials or cartridges. It also has the same vapor-phase hydrogen peroxide and clean-in-place (CIP) systems as other Vanrx Workcells.