The Vanrx Microcell Vial Filling Machine can fill pharmaceutical vials from 2R-50R. The Vanrx Microcell Vial Filler is for aseptic filling of pharmaceutical vials, focused on manufacturing clinical trial supplies and personalized medicines like cell therapies and gene therapies. It is a gloveless robotic isolator for aseptic filling.

Vial filling machine for personalized medicines and drug development

What is the Microcell Vial Filler?

The Vanrx Microcell is a fully integrated gloveless robotic isolator for pharmaceutical vial filling that can be used to make clinical trial supplies and develop new products. These include autologous cell therapies and personalized medicines.

The Microcell can help bring drug products to market faster by providing cost-effective, flexible filling capacity.

This new vial filling machine replaces manual filling and small-volume filling machines that combine with biosafety cabinets, RABS or isolators. These options can be expensive, and difficult and time-consuming to integrate.


Microcell Vial Filler benefits

  • Cost-effective

    Build clinical and development filling capacity at a lower cost and in less time.

  • Agile

    Fill up to four products in a single day. Can fill 2R-50R nested vials with toolless changeover and decontamination in 15 minutes.

  • Reduced risk

    Gloveless isolator eliminates operator error and buffers operators from drug products.

  • Easy to get started

    The Microcell is easy to learn and simple to operate.

  • Compact

    Can fit in a small space with little supporting infrastructure.

Vanrx Microcell Vial Filler Specifications



Up to 300 units per load / 1,200 units possible in 8-hour shift

Fill volume

0.1 – 50 mL (2R – 50R)

Pump type


Pump accuracy

±0.5% (±1.0% below 1 mL)

In-process (IPC) weigh

Programmable up to 100% of vials

Product contact materials

fill path assembly only (single-use)

Container / closure

2R-50R pre-sterilized nested vials and press-fit closures with industry standard 13/20mm stoppers.


Full 316L stainless steel interior and robotics

Interior classification

Grade A

Exterior classification

Grade C or D (depending on regulations)

Control system

21 CFR Part 11 compliant


1.966m wide x 1.688m long x 2.2m high (6’5″ x 5’5″ x 7’2″)

Required floor space

13m2 (140 sq./ ft.)


208-240V VAC

Compressed air

6 Bar clean, dry air


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Microcell Use Case: Biopharma

The Vanrx Microcell Vial Filler changes the economics of aseptic filling for clinical trials and product development. Multiple development candidates can come to market faster by bringing these activities in-house, and at a lower cost than outsourcing.

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Microcell Use Case: Cell therapies and personalized medicines

The Microcell Vial Filler can reduce your critical vein-to-vein time by allowing GMP manufacturing of personalized therapies.

Fast start-up and decontamination times allow Microcells to be ready when needed, and to change over quickly to the next patient’s therapy. Single-use consumables, including filling needles and product bags eliminate cross-contamination. Robotic filling eliminates operator error from manual processes. A standard machine design allows scale to be added as products succeed in trials and are commercially approved.

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Scale up to the SA25 Aseptic Filling Workcell

When your products succeed in early trials and need to move to higher volume late-stage trials or commercial manufacturing, the process is easily scaled to the Vanrx SA25 Aseptic Filling Workcell.

The SA25 is capable of filling the same vials and closures used in the Workcell, or can also process syringes and cartridges if the dosage format changes for your commercial launch. The same gloveless robotic approach is used across the full line of Vanrx Aseptic Workcells.

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