The Vanrx Microcell is a fully integrated gloveless robotic isolator for pharmaceutical vial filling that can be used to make clinical trial supplies and develop new products. These include autologous cell therapies and personalized medicines.
The Microcell can help bring drug products to market faster by providing cost-effective, flexible filling capacity.
This new vial filling machine replaces manual filling and small-volume filling machines that combine with biosafety cabinets, RABS or isolators. These options can be expensive, and difficult and time-consuming to integrate.
Build clinical and development filling capacity at a lower cost and in less time.
Fill up to four products in a single day. Can fill 2R-50R nested vials with toolless changeover and decontamination in 15 minutes.
Gloveless isolator eliminates operator error and buffers operators from drug products.
The Microcell is easy to learn and simple to operate.
Can fit in a small space with little supporting infrastructure.
Specification |
|
Throughput |
Up to 300 units per load / 1,200 units possible in 8-hour shift |
Fill volume |
0.1 – 100 mL |
Filling accuracy |
±0.5% (±1.0% below 1 mL) |
In-process (IPC) weigh |
Programmable up to 100% of vials |
Filling needle and flow path |
Single-use pre-sterilized |
Container / closure |
2R-50R pre-sterilized nested vials and press-fit closures with industry standard 13/20mm stoppers. |
Materials |
Full 316L stainless steel interior and robotics |
Interior classification |
ISO 5 or better |
Exterior classification |
ISO 8 / Grade C or D (depending on regulations) |
Pump type |
Peristaltic |
Control System |
21 CFR Part 11 compliant |
Dimensions |
1.70m wide x 1.5m long x 2.2m high (5.6′ x 4.9′ x 7.2′) |
Required floor space |
13m2 |
Electrical |
208-240V VAC |
Compressed air |
6 Bar clean, dry air |
Sep 4 - Sep 7, 2018
Boston, MA, USA
827
Sep 26 - Sep 26, 2018
Foxborough, MA, USA
E152 (East Hall)
Oct 9 - Oct 11, 2018
Madrid, Spain
4F114
The Vanrx Microcell Vial Filler changes the economics of aseptic filling for clinical trials and product development. Multiple development candidates can come to market faster by bringing these activities in-house, and at a lower cost than outsourcing.
Learn MoreThe Microcell Vial Filler can reduce your critical vein-to-vein time by allowing GMP manufacturing of personalized therapies.
Fast start-up and decontamination times allow Microcells to be ready when needed, and to change over quickly to the next patient’s therapy. Single-use consumables, including filling needles and product bags eliminate cross-contamination. Robotic filling eliminates operator error from manual processes. A standard machine design allows scale to be added as products succeed in trials and are commercially approved.
Learn MoreWhen your products succeed in early trials and need to move to higher volume late-stage trials or commercial manufacturing, the process is easily scaled to the Vanrx SA25 Aseptic Filling Workcell.
The SA25 is capable of filling the same vials and closures used in the Workcell, or can also process syringes and cartridges if the dosage format changes for your commercial launch. The same gloveless robotic approach is used across the full line of Vanrx Aseptic Workcells.
Learn more